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Effect of paraxanthine on free fatty acid
(FFA) mobilization after intravenous caffeine administration in
humans.
"Hetzler, R.K.; Knowlton, R.G.; Somani, G.M.; Brown,
D.D.; Perkins, R.M. J Appl Physiol 1990; 68(1): 44-7
Because it has (previously) been shown that it takes much more
caffeine to cause fat mobilization in vitro than in vivo, it has
been suggested that there may be an active metabolite working
with caffeine causing an increase in lipolysis in vivo. To
determine the relationship between the appearance of paraxanthine
(caffeine's major dimethylxanthine metabolite) and free fatty
acid (FFA) mobilization after intravenous caffeine
administration, 10 men were studied at rest after receiving a
dose of 4 mg/kg lean body mass. Venous blood samples were
obtained before dosing and at minutes 5, 10, 15, 30, 45, 60, 90,
120, 150, and 180. Serum levels of FFA, glycerol, caffeine,
and paraxanthine were determined in duplicate.
Concentrations of FFA and glycerol were corrected for plasma
volume changes. A high negative correlation was seen
between decreases in caffeine and increases in FFA (r=-0.90) and
a high positive correlation was seen between the appearance of
paraxanthine and FFA (r=0.93). It was concluded that
paraxanthine may play a role in increased lipolysis after
caffeine administration in humans."
Note from The Tea Man:
| Caffeine
contents per 6 oz cup |
mg. |
| Espresso Coffee |
60-90 |
| Drip Coffee |
60-180 |
Black Tea
(based upon species of tea bush) |
25-110 |
Semi-black (Oolong) Tea
(based upon species & % of oxidation) |
12-55 |
Green Tea
(based upon species/sub-species & % of oxidation |
6-16 |
Therefore, 1 cup of coffee = approximately 3 cups of black
tea, 4 cups of semi-black tea and 5 cups of green tea
Prepared by and property of:
"The Tea Man"
May not be reproduced in whole or in part without written consent
of: "The Tea Man"
Copyright © April 1999
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